The Bills are 9-2, their best start since 1992, and with a win would clinch their fifth straight AFC East title.

San Francisco's starting quarterback missed last week's loss to the Packers. Here's the latest on whether he'll play in primetime on Sunday.

Coming into the 2024 NFL season, it wouldn't have been out of the ordinary to find a Super Bowl prediction featuring the ...

On Saturday night, ESPN's Adam Schefter reported that San Francisco 49ers quarterback Brock Purdy, officially listed as ...

QB Brock Purdy injured his shoulder in Week 11 against the Seattle Seahawks and wound up missing the team’s blowout Week 12 ...

The results were ugly for the San Francisco 49ers last week against the Green Bay Packers without starting quarterback Brock ...

Fantasy managers may need to proceed with caution before placing San Francisco's offensive players in their lineup this week.

The Buffalo Bills will host the San Francisco 49ers at Highmark Stadium in Orchard Park, New York, on Sunday, December 1, at ...

The San Francisco 49ers and Buffalo Bills are set to face-off in the Week 13 edition of Sunday Night Football. Before the season began, this matchup was circled ...

It’s not like he was throwing at game speed, but the sight of Brock Purdy throwing the ball during warmups Friday was encouraging before the 49ers left on a trip to Buffalo for a Sunday night game ...

While Purdy's return is promising, the 49ers face significant roster challenges with multiple injuries, including Nick Bosa ...

Three things I’m pondering as the Bills return from their bye for the stretch run… Mila-No More Waiting Matt Milano is ...