It's Buffalo Bills vs San Francisco 49ers in Week 13 of the NFL season. Can Josh Allen and company outduel Christian McCaffery and Deebo Samuel?

Back-to-back blowout losses and another injury to star back Christian McCaffrey might just be the final blow to the dwindling ...

Roster management is the single most crucial in-season task for fantasy football managers. Knowing which players to let go is as important as adding the right guys. Which players find themselves on ...

Head coach Kyle Shanahan shared the latest injury and team updates emerging from the San Francisco 49ers Week 13 matchup ...

Missouri receiver Luther Burden III is passing on his senior season and declaring for the NFL Draft. As a result, he will not ...

The San Francisco 49ers hosted a fan-focused event with the 49ers Pride Fan Group and PLUS (LGBTQ+) ERG to discuss being out ...

See what Kyle Shanahan, Brock Purdy, Sean McDermott and Josh Allen had to say following the Week 13 primetime contest.

Jerry Jeudy has hit out at Steve Smith amid a resurgence in form, and Terrell Owens could be in line for a similar sort of ...

But now it is back to the drawing board, not only for McCaffrey, but the 49ers at large. His injury, of course, is just one ...

Deebo Samuel is one of the names to watch. The 6th year wide receiver is set to see his contract balloon in 2025, as his ...

One last note of the bizarre: Niners tight end and eternal optimist George Kittle referenced a speech Shanahan gave back in ...

The 49ers just lost 35-10 to the Buffalo Bills. Now the 49ers are 5-7 and all alone in last place in the NFC West. Here are their grades for this per ...